Here, presented without comment, are the top 100 Major League Equivalent kwERA's for minor league pitchers during the 2012 season (pitchers with more than 100 batters faced). Players are listed by the highest level team for which they played in 2012.
Note: kwERA = 5.4-12*(K-BB)/PA
| Name | Team | Age | TBF | eqK% | eqBB% | kwEQA |
| Straily, Daniel | Athletics (AAA) | 23 | 602 | 26 | 9 | 3.30 |
| Ely, John | Dodgers (AAA) | 26 | 682 | 21 | 7 | 3.63 |
| Griffin, A.J. | Athletics (AAA) | 24 | 402 | 19 | 5 | 3.82 |
| Chavez, Jesse | Blue Jays (AAA) | 28 | 429 | 19 | 6 | 3.88 |
| Leblanc, Wade | Marlins (AAA) | 27 | 403 | 19 | 6 | 3.90 |
| Irwin, Phil | Pirates (AAA) | 25 | 532 | 18 | 6 | 3.90 |
| Miller, Shelby | Cardinals (AAA) | 21 | 599 | 22 | 10 | 3.91 |
| Smith, Burch | Padres (A+) | 22 | 534 | 19 | 7 | 3.91 |
| Seddon, Chris | Indians (AAA) | 28 | 494 | 19 | 6 | 3.92 |
| Wilk, Adam | Tigers (AAA) | 24 | 595 | 18 | 6 | 3.94 |
| Workman, Brandon | Red Sox (AA) | 23 | 555 | 18 | 6 | 3.94 |
| Blackburn, Clayton | Giants (A) | 19 | 531 | 17 | 5 | 3.94 |
| Cingrani, Tony | Reds (AA) | 22 | 570 | 24 | 11 | 3.95 |
| Barnes, Matt | Red Sox (A+) | 22 | 480 | 20 | 8 | 3.95 |
| Petit, Yusmeiro | Giants (AAA) | 27 | 701 | 18 | 6 | 3.97 |
| Fernandez, Jose | Marlins (A+) | 19 | 513 | 22 | 10 | 4.00 |
| Bauer, Trevor | Diamondbacks (AAA) | 21 | 548 | 25 | 13 | 4.01 |
| Font, Wilmer | Rangers (AA) | 22 | 406 | 26 | 14 | 4.01 |
| Morgan, Adam | Phillies (AA) | 22 | 633 | 20 | 8 | 4.02 |
| Cabrera, Edwar | Rockies (AAA) | 24 | 511 | 20 | 8 | 4.03 |
| Redmond, Todd | Reds (AAA) | 27 | 624 | 19 | 7 | 4.06 |
| Hendricks, Kyle | Cubs (A+) | 22 | 590 | 15 | 4 | 4.06 |
| Heston, Chris | Giants (AA) | 24 | 595 | 19 | 8 | 4.07 |
| Lyons, Tyler | Cardinals (AAA) | 24 | 640 | 18 | 7 | 4.09 |
| Anderson, Chase | Diamondbacks (AA) | 24 | 422 | 19 | 8 | 4.09 |
| Germano, Justin | Red Sox (AAA) | 29 | 409 | 14 | 4 | 4.11 |
| Nolin, Sean | Blue Jays (AA) | 22 | 404 | 20 | 9 | 4.12 |
| Vandenhurk, Rick | Pirates (AAA) | 27 | 547 | 19 | 8 | 4.13 |
| Locke, Jeff | Pirates (AAA) | 24 | 585 | 19 | 9 | 4.13 |
| Skaggs, Tyler | Diamondbacks (AAA) | 20 | 503 | 20 | 9 | 4.13 |
| Montero, Rafael | Mets (A+) | 21 | 479 | 16 | 6 | 4.14 |
| Maness, Seth | Cardinals (AA) | 23 | 680 | 12 | 2 | 4.15 |
| Buckel, Cody | Rangers (AA) | 20 | 572 | 21 | 11 | 4.16 |
| Castillo, Jorge | NULL | 30 | 464 | 19 | 9 | 4.17 |
| Moscoso, Guillermo | Rockies (AAA) | 28 | 434 | 17 | 7 | 4.18 |
| Nicolino, Justin | Blue Jays (A) | 20 | 495 | 16 | 6 | 4.19 |
| Nuno, Vidal | Yankees (AA) | 24 | 567 | 17 | 7 | 4.23 |
| Werner, Andrew | Padres (AAA) | 25 | 529 | 17 | 7 | 4.24 |
| Ridings, Matt | Royals (A+) | 24 | 414 | 16 | 6 | 4.24 |
| Martin, Cody | Braves (A+) | 22 | 445 | 20 | 10 | 4.24 |
| Kluber, Corey | Indians (AAA) | 26 | 545 | 20 | 11 | 4.25 |
| Gayhart, Jared | Tigers (AA) | 25 | 401 | 20 | 10 | 4.25 |
| Thornburg, Tyler | Brewers (AAA) | 23 | 469 | 19 | 9 | 4.26 |
| Brewer, Charles | Diamondbacks (AAA) | 24 | 678 | 16 | 6 | 4.27 |
| Holmberg, David | Diamondbacks (AA) | 20 | 706 | 16 | 7 | 4.27 |
| Wilson, Tyler | Orioles (A+) | 22 | 575 | 17 | 8 | 4.27 |
| Mchugh, Collin | Mets (AAA) | 25 | 615 | 18 | 9 | 4.28 |
| Ramirez, Roberto | NULL | 40 | 563 | 15 | 6 | 4.28 |
| Vasquez, Esmerling | Twins (AAA) | 28 | 403 | 21 | 11 | 4.29 |
| Pino, Yohan | Blue Jays (AAA) | 28 | 611 | 15 | 6 | 4.29 |
| Dickson, Brandon | Cardinals (AAA) | 27 | 594 | 15 | 5 | 4.29 |
| Pill, Tyler | Mets (A+) | 22 | 466 | 16 | 7 | 4.29 |
| Martin, J.D. | Marlins (AAA) | 29 | 571 | 13 | 4 | 4.30 |
| O'Connor, Mike | Yankees (AAA) | 31 | 464 | 17 | 8 | 4.30 |
| Albers, Andrew | Twins (AA) | 26 | 416 | 14 | 5 | 4.30 |
| Yan, Esteban | NULL | 37 | 585 | 14 | 5 | 4.30 |
| Magill, Matthew | Dodgers (AA) | 22 | 623 | 21 | 12 | 4.31 |
| Verrett, Logan | Mets (A+) | 22 | 425 | 15 | 6 | 4.31 |
| Espino, Paolo | Indians (AAA) | 25 | 516 | 18 | 9 | 4.33 |
| Hendriks, Liam | Twins (AAA) | 23 | 412 | 17 | 8 | 4.33 |
| Roark, Tanner | Nationals (AAA) | 25 | 645 | 18 | 9 | 4.33 |
| Syndergaard, Noah | Blue Jays (A) | 19 | 420 | 20 | 11 | 4.34 |
| Oberholtzer, Brett | Astros (AAA) | 23 | 719 | 15 | 7 | 4.35 |
| Burgos, Hiram | Brewers (AAA) | 24 | 672 | 18 | 9 | 4.36 |
| Boscan, Wilfredo | Rangers (AA) | 22 | 405 | 17 | 9 | 4.36 |
| Ventura, Yordano | Royals (AA) | 21 | 479 | 21 | 12 | 4.36 |
| Gonzalez, Mario | NULL | 27 | 497 | 15 | 7 | 4.36 |
| Cole, A.J. | Athletics (A+) | 20 | 558 | 16 | 7 | 4.36 |
| Odorizzi, Jake | Royals (AAA) | 22 | 612 | 18 | 10 | 4.37 |
| Radeke, Mason | Indians (AA) | 22 | 474 | 17 | 8 | 4.37 |
| Grimm, Justin | Rangers (AAA) | 23 | 542 | 15 | 7 | 4.38 |
| Rienzo, Andre | White Sox (AAA) | 24 | 429 | 21 | 12 | 4.38 |
| Shirek, Charlie | White Sox (AAA) | 26 | 701 | 13 | 5 | 4.39 |
| Berger, Eric | Indians (AAA) | 26 | 479 | 18 | 9 | 4.39 |
| Harvey, Matt | Mets (AAA) | 23 | 473 | 20 | 12 | 4.39 |
| Weber, Thad | Tigers (AAA) | 27 | 614 | 15 | 7 | 4.39 |
| Schlosser, Gus | Braves (A+) | 23 | 669 | 15 | 7 | 4.39 |
| Nieve, Fernando | Dodgers (AAA) | 29 | 560 | 17 | 9 | 4.40 |
| Cole, Gerrit | Pirates (AAA) | 21 | 549 | 19 | 11 | 4.40 |
| Grube, Jarrett | Mariners (AAA) | 30 | 425 | 15 | 7 | 4.41 |
| Gamboa, Eddie | Orioles (AAA) | 27 | 475 | 14 | 6 | 4.41 |
| Fernandez, Anthony | Mariners (AA) | 22 | 681 | 15 | 7 | 4.42 |
| Billings, Bruce | Athletics (AAA) | 26 | 571 | 17 | 9 | 4.43 |
| Wheeler, Zack | Mets (AAA) | 22 | 608 | 20 | 12 | 4.43 |
| Santiago, Andres | Dodgers (AA) | 22 | 469 | 19 | 11 | 4.44 |
| Karns, Nathan | Nationals (A+) | 24 | 457 | 23 | 15 | 4.46 |
| Degrom, Jacob | Mets (A+) | 24 | 450 | 14 | 6 | 4.47 |
| Andriese, Matt | Padres (A+) | 22 | 603 | 16 | 9 | 4.47 |
| Duckworth, Brandon | Red Sox (AAA) | 36 | 462 | 17 | 9 | 4.48 |
| Scahill, Rob | Rockies (AAA) | 25 | 693 | 20 | 12 | 4.48 |
| Struck, Nicholas | Cubs (AA) | 22 | 649 | 16 | 9 | 4.49 |
| Castro, Simon | White Sox (AAA) | 24 | 497 | 14 | 7 | 4.50 |
| Schwinden, Chris | Yankees (AAA) | 25 | 554 | 15 | 8 | 4.50 |
| Treinen, Blake | Athletics (A+) | 23 | 448 | 14 | 7 | 4.51 |
| Schmidt, Nick | Rockies (AAA) | 26 | 630 | 16 | 9 | 4.52 |
| Richmond, Scott | Blue Jays (AAA) | 32 | 595 | 16 | 9 | 4.52 |
| Hald, Kyle | Cardinals (A+) | 23 | 578 | 13 | 6 | 4.52 |
| Campos, Francisco | NULL | 39 | 449 | 15 | 8 | 4.53 |
| Branham, Matthew | Padres (A+) | 24 | 459 | 17 | 9 | 4.53 |
| Tropeano, Nick | Astros (A+) | 21 | 656 | 17 | 10 | 4.53 |
